In mice, KIR+ T cells have been shown to regulate rogue T cells that cause autoimmune disease. Now we know about KIR+ T cells in humans and how important they are to immune tolerance in humans
Forgive me if I don’t understand the technical details being discussed here but it appears to me that the results show gluten may be helpful for those suffering from celiac disease. Is that correct? Isn’t that the exact opposite of what we’ve been told for years?
One of the reasons I never took the clot shot is that I’m aware that everything about the workings of the immune system is NOT fully understood. Medical science is figuring out new aspects every day...so don’t gamble with some novel technology!
Like Andy, I’m not sure about how laypeople should interpret this result as it pertains to gluten in our diets. So is gluten beneficial or not? James, please clarify.
My 17 yr old daughter was diagnosed with celiac at age 5. Can you explain it layman's terms? Both my girls are positive for celiac-associated allele(s).
My celiac daughter has a genetic risk of Moderate 1:35
HLA DQ alleles detected DQA1*05:CCBGE, 05:CCBGF
DQB1*02:CCBGG, 03:CCBGH
HLA allele intepretation based on IMGT/HLA database version 3.37.0
The patient is positive for DQ2. Celiac Disease risk from
the HLA DQA/DQB genotype is approximately 1:35 (2.9%)
DQ2 POSITIVE, two copies
DQB1*02:01/02:02 POSITIVE, one copy
My youngest Low 1:210
HLA DQ alleles detected DQA1*01:CCBEP, 02:DWH
DQB1*02:CCBDS, 06:CCFGY
HLA allele intepretation based on IMGT/HLA database version 3.37.0
The patient is positive for DQB1*02, one half of the DQ2
heterodimer. The Celiac Disease risk from the HLA DQA/DQB
genotype is approximately 1:210 (0.5%). This is less than
Stanford University Research: New Autoimmune Regulator Found in Humans: KIR+ T-Cells
Love the comic representations of cells.
Forgive me if I don’t understand the technical details being discussed here but it appears to me that the results show gluten may be helpful for those suffering from celiac disease. Is that correct? Isn’t that the exact opposite of what we’ve been told for years?
Thanks, Andy!
Cool. Glad you called out the troll too.
One of the reasons I never took the clot shot is that I’m aware that everything about the workings of the immune system is NOT fully understood. Medical science is figuring out new aspects every day...so don’t gamble with some novel technology!
Like Andy, I’m not sure about how laypeople should interpret this result as it pertains to gluten in our diets. So is gluten beneficial or not? James, please clarify.
JLW - P53 activation and immune dysregulation at work.
My 17 yr old daughter was diagnosed with celiac at age 5. Can you explain it layman's terms? Both my girls are positive for celiac-associated allele(s).
My celiac daughter has a genetic risk of Moderate 1:35
HLA DQ alleles detected DQA1*05:CCBGE, 05:CCBGF
DQB1*02:CCBGG, 03:CCBGH
HLA allele intepretation based on IMGT/HLA database version 3.37.0
The patient is positive for DQ2. Celiac Disease risk from
the HLA DQA/DQB genotype is approximately 1:35 (2.9%)
DQ2 POSITIVE, two copies
DQB1*02:01/02:02 POSITIVE, one copy
My youngest Low 1:210
HLA DQ alleles detected DQA1*01:CCBEP, 02:DWH
DQB1*02:CCBDS, 06:CCFGY
HLA allele intepretation based on IMGT/HLA database version 3.37.0
The patient is positive for DQB1*02, one half of the DQ2
heterodimer. The Celiac Disease risk from the HLA DQA/DQB
genotype is approximately 1:210 (0.5%). This is less than
the 1% risk in the general population.
DQA1*05:01/05:05 NEGATIVE
DQB1*02:01/02:02 POSITIVE, one copy
So now the I would like to build more KIR+CD8+ T cells and how is that possible? Diet, medicine,
exercise, stem cells?
So now the I would like to build more KIR+CD8+ T cells and how is that possible? Diet, medicine,
exercise, stem cells?
🚨🚨🚨 please be aware https://open.substack.com/pub/sagehana/p/dear-substack-readers-and-writers?r=ykqw5&utm_medium=ios&utm_campaign=post