What is the fate of injected aluminum? I know some stays where it is injected, and some is transported to the brain and other places by macrophages. I suppose the counterargument to exceeding the FDA's limit is that it is not comparable to intravenous route.
Edit: The FDA doc actually says parenteral, not intravenous. That is more concern…
What is the fate of injected aluminum? I know some stays where it is injected, and some is transported to the brain and other places by macrophages. I suppose the counterargument to exceeding the FDA's limit is that it is not comparable to intravenous route.
Edit: The FDA doc actually says parenteral, not intravenous. That is more concerning. But it also raises the question as to why they would have the same dose limit for all parenteral routes. Now i suppose the main counterargument would be that they are describing long-term administraiton. But 20 days is nothing to scoff at. And who is to say that stacking it all up on a specific day(s) isn't worse.
Also:
“Aluminum may reach toxic levels with prolonged parenteral administration if kidney function is impaired. Premature neonates are particularly at risk because their kidneys are immature, and they require large amounts of calcium and phosphate solutions, which contain aluminum"
What is the fate of injected aluminum? I know some stays where it is injected, and some is transported to the brain and other places by macrophages. I suppose the counterargument to exceeding the FDA's limit is that it is not comparable to intravenous route.
Edit: The FDA doc actually says parenteral, not intravenous. That is more concerning. But it also raises the question as to why they would have the same dose limit for all parenteral routes. Now i suppose the main counterargument would be that they are describing long-term administraiton. But 20 days is nothing to scoff at. And who is to say that stacking it all up on a specific day(s) isn't worse.
Also:
“Aluminum may reach toxic levels with prolonged parenteral administration if kidney function is impaired. Premature neonates are particularly at risk because their kidneys are immature, and they require large amounts of calcium and phosphate solutions, which contain aluminum"
So...that is in addition to other exposures???
Yes