I was meandering through papers on NAD+, Sirtuins, and Niacin, as relates to cancer and these vaccines; (looking for potential 'smoking-gun' studies); when the fact of Niacinamide being the preferred NAD+ precursor during cancer-treatment, due to it not requiring Glutamine in the synthesis of NAD+, got me off those search-terms and onto …
I was meandering through papers on NAD+, Sirtuins, and Niacin, as relates to cancer and these vaccines; (looking for potential 'smoking-gun' studies); when the fact of Niacinamide being the preferred NAD+ precursor during cancer-treatment, due to it not requiring Glutamine in the synthesis of NAD+, got me off those search-terms and onto the Glutamine metabolism track.
Papers found so far lead me to hypothesize that if these vaccines are destabilizing Glutamine metabolism, that is sufficient to answer at least some of the cancers. Interestingly, one paper revealed a Glutamine deficiency in advanced hospital Covid-cases. Competition for Glutamine between T-cells and Tumor-cells is well documented.
One question is what if we're mass-vaccinating into a Glutamine-deficient aged-population; with its preexisting propensity for cancer metabolism? At one end, they're not making it out of the hospital or nursing home. At the other, with weakened or altered T-cell signaling due to viral infection, T-cells lose the competition for Glutamine. Another question goes back to the related NAD+ metabolism. What if we're mass-vaccinating into a NAD+ deficient and/or a Niacin-deficient population? There's no 'discounting' for any of these considerations prior to shots being administered. What good is it to have our scientists find the commonality of Glutamine deficiency in advanced Covid cases and not notify everyone in headlines and covers of grocery store magazines?
Excerpts from an article by Dr. Thomas Levy:
The involvement of niacin in preventing cancer and chemotherapeutic side effects is not commonly recognized, but decades of research has established that niacin deficiency is common in cancer patients and cancer patients require larger amounts of niacin to correct deficiency. [4]
Generally, studies indicate that NAD functions as a preservative protecting cellular DNA from mutation and also preventing mutated cancer cells from surviving. Niacin deficiency promotes cancer by decreasing genomic stability, increasing the chances both for mutation and survival of mutated cancer cells.
Studies indicate that niacin deficiency delays DNA repair, promotes accumulation of DNA strand breaks, chromosomal translocations, telomere erosion typical of aging, and promotes cancer. Rat model studies indicate that most of these aspects of genomic instability are all minimized by the recommended levels of niacin. [5] Niacin deficiency also increases levels of the tumor suppressor p53. [6] Studies in mice indicate that mild niacin deficiency can cause an increased incidence of ultraviolet-B induced skin cancer. [7]
This review of 183 studies does a nice job of bringing together NAD+, PARP enzymes, Sirtuins, DNA repair, Cytotoxicity, and T-cell considerations.
NAD+-consuming enzymes in immune defense against viral infection
I was meandering through papers on NAD+, Sirtuins, and Niacin, as relates to cancer and these vaccines; (looking for potential 'smoking-gun' studies); when the fact of Niacinamide being the preferred NAD+ precursor during cancer-treatment, due to it not requiring Glutamine in the synthesis of NAD+, got me off those search-terms and onto the Glutamine metabolism track.
Papers found so far lead me to hypothesize that if these vaccines are destabilizing Glutamine metabolism, that is sufficient to answer at least some of the cancers. Interestingly, one paper revealed a Glutamine deficiency in advanced hospital Covid-cases. Competition for Glutamine between T-cells and Tumor-cells is well documented.
One question is what if we're mass-vaccinating into a Glutamine-deficient aged-population; with its preexisting propensity for cancer metabolism? At one end, they're not making it out of the hospital or nursing home. At the other, with weakened or altered T-cell signaling due to viral infection, T-cells lose the competition for Glutamine. Another question goes back to the related NAD+ metabolism. What if we're mass-vaccinating into a NAD+ deficient and/or a Niacin-deficient population? There's no 'discounting' for any of these considerations prior to shots being administered. What good is it to have our scientists find the commonality of Glutamine deficiency in advanced Covid cases and not notify everyone in headlines and covers of grocery store magazines?
Excerpts from an article by Dr. Thomas Levy:
The involvement of niacin in preventing cancer and chemotherapeutic side effects is not commonly recognized, but decades of research has established that niacin deficiency is common in cancer patients and cancer patients require larger amounts of niacin to correct deficiency. [4]
Generally, studies indicate that NAD functions as a preservative protecting cellular DNA from mutation and also preventing mutated cancer cells from surviving. Niacin deficiency promotes cancer by decreasing genomic stability, increasing the chances both for mutation and survival of mutated cancer cells.
Studies indicate that niacin deficiency delays DNA repair, promotes accumulation of DNA strand breaks, chromosomal translocations, telomere erosion typical of aging, and promotes cancer. Rat model studies indicate that most of these aspects of genomic instability are all minimized by the recommended levels of niacin. [5] Niacin deficiency also increases levels of the tumor suppressor p53. [6] Studies in mice indicate that mild niacin deficiency can cause an increased incidence of ultraviolet-B induced skin cancer. [7]
This review of 183 studies does a nice job of bringing together NAD+, PARP enzymes, Sirtuins, DNA repair, Cytotoxicity, and T-cell considerations.
NAD+-consuming enzymes in immune defense against viral infection
https://portlandpress.com/biochemj/article/478/23/4071/230375/NAD-consuming-enzymes-in-immune-defense-against